Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 15/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE6C | P51160 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11389378 | 0.90 | PDE5A (0.46) | PDE5APDE2APDE9APDE4APDE6C | |
| SCHEMBL11374918 | 0.90 | NPSR1 (0.42) | PDE5APARG | |
| SCHEMBL11376235 | 0.88 | NPSR1 (0.44) | PDE5AABCC5PARG | |
| SCHEMBL11381837 | 0.87 | PDE5A (0.53) | PDE5APDE2APDE9APDE4APDE6C | |
| SCHEMBL11384755 | 0.86 | PDE5A (0.42) | PDE5A | |
| SCHEMBL11559725 | 0.82 | TP53 (0.44) | PDE5AKDM4E | |
| SCHEMBL11381526 | 0.82 | NPSR1 (0.50) | PDE4AKDM4E | |
| SCHEMBL11390124 | 0.81 | PDE5A (0.41) | PDE5AKDM4E | |
| SCHEMBL11384783 | 0.81 | PDE5A (0.48) | PDE5APDE6C | |
| SCHEMBL11550616 | 0.80 | GUSB (0.51) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |