Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 14/20 | 0.47 |
| ▸ | WDR5 | P61964 | 2/20 | 0.44 |
| ▸ | ABCC5 | O15440 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381837 | 0.90 | PDE5A (0.53) | PDE5AWDR5KDM4E | |
| SCHEMBL11384783 | 0.89 | PDE5A (0.48) | PDE5AWDR5 | |
| SCHEMBL11377346 | 0.88 | NPSR1 (0.46) | LMNAHTTHIF1ANPSR1MCOLN3 | |
| SCHEMBL11386259 | 0.87 | PDE5A (0.53) | PDE5AWDR5 | |
| SCHEMBL11376235 | 0.85 | NPSR1 (0.44) | LMNAHTTHIF1ANPSR1MCOLN3 | |
| SCHEMBL11375179 | 0.82 | PDE5A (0.45) | PDE5AKDM4E | |
| SCHEMBL11382440 | 0.82 | ALDH1A1 (0.50) | LMNAHTTHIF1ANPSR1MCOLN3 | |
| SCHEMBL11549969 | 0.81 | GUSB (0.49) | LMNAPDE5AKDM4E | |
| SCHEMBL11380722 | 0.80 | PDE5A (0.59) | LMNAHIF1APDE5AKDM4E | |
| SCHEMBL11389378 | 0.79 | PDE5A (0.46) | HTTPDE5AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |