Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390974 | 0.76 | LMNA (0.43) | SMN1; SMN2POLBMAPK1RAB9ALMNA | |
| SCHEMBL11390971 | 0.75 | LMNA (0.42) | SMN1; SMN2POLBMAPK1RAB9ALMNA | |
| SCHEMBL11227476 | 0.64 | ALDH1A1 (0.46) | SMN1; SMN2POLBMAPK1LMNAMAPT | |
| SCHEMBL11873585 | 0.61 | MAOB (0.53) | SMN1; SMN2POLBMAPK1RAB9ALMNA | |
| SCHEMBL11563707 | 0.56 | MAOB (0.51) | SMN1; SMN2POLBLMNAMAPTKDM4E | |
| SCHEMBL11560839 | 0.55 | LMNA (0.62) | SMN1; SMN2RAB9ALMNAMAPTKDM4E | |
| SCHEMBL31451032 | 0.55 | NPC1 (0.48) | SMN1; SMN2POLBRAB9ALMNAMAPT | |
| SCHEMBL19995853 | 0.55 | ALDH1A1 (0.44) | SMN1; SMN2POLBRAB9AMAPTMEN1 | |
| SCHEMBL11391881 | 0.55 | MAOB (0.63) | SMN1; SMN2MAPTRECQLMAOBALDH1A1 | |
| SCHEMBL8682316 | 0.54 | KDM4E (0.41) | SMN1; SMN2POLBMAPK1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216155-A | 3-GLYCOLOYLAMINO-4-OXO-4H-1-BENZOPYRAN; ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-08-05 | — | — | US | claimed |
| US-4288450-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| US-4216155-A | 3-GLYCOLOYLAMINO-4-OXO-4H-1-BENZOPYRAN; ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |