Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MMP14 | P50281 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198303 | 0.84 | MAPT (0.54) | KDM4EMAPTALDH1A1LMNAMEN1 | |
| Methane SCHEMBL28257008 | 0.82 | MAPT (0.52) | KDM4EMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL7014902 | 0.77 | NR4A2 (0.48) | KDM4EMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL30906615 | 0.76 | KDM4E (0.50) | KDM4EMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL4554547 | 0.74 | PSMD14 (0.56) | KDM4EMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL2390627 | 0.74 | LMNA (0.56) | KDM4EMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL276385 | 0.73 | METAP2 (0.54) | KDM4EMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL29577533 | 0.73 | METAP2 (0.54) | KDM4EMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL1901071 | 0.73 | KDM4E (0.46) | KDM4EMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL1773094 | 0.73 | PRMT5 (0.53) | KDM4EMAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075478-B1 | PHENYLUREA AND PHENYLTHIO UREA DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2003-04-16 | — | — | EP | claimed |
| US-12545682-B2 | Heterocyclic derivatives as P2X7 receptor antagonists | BREYE THERAPEUTICS APS (DK) | 2026-02-10 | — | — | US | disclosed |
| US-20250360145-A1 | CSF-1R INHIBITORS AND USES THEREOF | MYROBALAN THERAPEUTICS INC (US) | 2025-11-27 | — | — | US | disclosed |
| US-12448368-B2 | Indole compounds as androgen receptor modulators | NIDO BIOSCIENCES, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| EP-4539933-A1 | CSF-1R INHIBITORS AND USES THEREOF | Myrobalan Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| US-20250122176-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2025-04-17 | — | — | US | disclosed |
| CN-119790038-A | CSF-1R inhibitors and uses thereof | 迈巴制药公司 | 2025-04-08 | — | — | CN | disclosed |
| US-20250092021-A9 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. | 2025-03-20 | — | — | US | disclosed |
| EP-4262975-B1 | HETEROCYCLIC DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | BREYE THERAPEUTICS APS (DK) | 2025-03-05 | — | — | EP | disclosed |
| WO-2025039979-A1 | PROTEIN ARGININE METHYLTRANSFERASE-5 INHIBITOR AND PHARMACEUTICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2025-02-27 | — | — | WO | disclosed |
| WO-2000047576-A1 | CINNAMIDE DERIVATIVES AS OREXIN-1 RECEPTORS ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2000-08-17 | — | — | WO | disclosed |
| US-5240916-A | Fungicides | DOWELANCO (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0060012-B1 | 4-HALO-1,8-NAPHTHYRIDINE DERIVATIVES USEFUL AS INTERMEDIATES AND PROCESSES FOR THEIR PREPARATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-29 | — | — | EP | disclosed |
| EP-0018735-B1 | 1,8-NAPHTHYRIDINE DERIVATIVES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-07-27 | — | — | EP | disclosed |
| US-4350817-A | 4-Cl, Br or I-3-Carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-21 | — | — | US | disclosed |
| EP-0060012-A1 | 4-Halo-1,8-naphthyridine derivatives useful as intermediates and processes for their preparation | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-15 | — | — | EP | disclosed |
| US-4347362-A | HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-08-31 | — | — | US | disclosed |
| US-4324893-A | 4-Amino-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-04-13 | — | — | US | disclosed |
| EP-0018735-A1 | 1,8-Naphthyridine derivatives, their preparation, pharmaceutical compositions containing them | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-11-12 | — | — | EP | disclosed |
| WO-1980002287-A1 | 1,8-NAPHTHYRIDINE DERIVATIVES | AMERICAN HOME PROD (US) | 1980-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122176-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | KDM4E 1654/4885MAPT 735/4885ALDH1A1 2325/4885 |
| US-20250360145-A1 | CSF-1R INHIBITORS AND USES THEREOF | CSF1R, CSF3R, IL1RN | KDM4E 3663/4885MAPT 2405/4885ALDH1A1 1248/4885 |
| US-20250092021-A9 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | KDM4E 1654/4885MAPT 735/4885ALDH1A1 2325/4885 |
| US-12448368-B2 | Indole compounds as androgen receptor modulators | AR, FSHR, ADRB3 | KDM4E 1533/4885MAPT 682/4885ALDH1A1 2697/4885 |
| US-12545682-B2 | Heterocyclic derivatives as P2X7 receptor antagonists | P2RX7, P2RX3, P2RX1 | KDM4E 3820/4885MAPT 4689/4885ALDH1A1 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.