Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15039281 | 0.80 | — | — | |
| SCHEMBL17745050 | 0.79 | CASP3 (0.37) | MAPTBLMBRD4MEN1KMT2A | |
| SCHEMBL15039273 | 0.77 | S100B (0.31) | — | |
| SCHEMBL5158945 | 0.73 | MAPT (0.51) | MAPTCASP1CASP7CYP3A4TP53 | |
| SCHEMBL123696 | 0.72 | MAPT (0.39) | MAPTCASP1CASP7CYP3A4TP53 | |
| SCHEMBL15020219 | 0.71 | CYP19A1 (0.36) | MAPTCASP1CASP7CYP3A4TP53 | |
| SCHEMBL13809514 | 0.71 | MAPT (0.36) | MAPTCASP1CASP7CYP3A4TP53 | |
| SCHEMBL15513377 | 0.71 | MAPK1 (0.43) | CASP7CYP3A4BRD4TSHRMEN1 | |
| SCHEMBL15022915 | 0.70 | DNM1 (0.50) | MAPTCASP1CASP7CYP3A4TP53 | |
| SCHEMBL16272076 | 0.69 | DNM1 (0.36) | MAPTCASP1CASP7CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260749-A | HAIR DYES | L'OREAL (FR) | 1981-04-07 | — | — | US | disclosed |
| US-4204059-A | HAIR DYES | L'OREAL (FR) | 1980-05-20 | — | — | US | disclosed |
| US-4084052-A | HAIR DYES | L'OREAL (FR) | 1978-04-11 | — | — | US | disclosed |
| US-4023926-A | Diaminobenzoquinones in hair dye compositions | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-05-17 | — | — | US | disclosed |