Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11392957 | 0.82 | MAPT (0.40) | MAPTGAASMN1; SMN2MEN1APAF1 | |
| SCHEMBL9499966 | 0.80 | GAA (0.47) | MAPTGAASMN1; SMN2GBA1ALDH1A1 | |
| SCHEMBL1152075 | 0.79 | MAPT (0.37) | MAPTGAASMN1; SMN2MEN1APAF1 | |
| Sulfuric Acid SCHEMBL9680698 | 0.77 | GAA (0.43) | MAPTGAASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL17745050 | 0.75 | CASP3 (0.37) | MAPTMEN1APAF1CASP3KMT2A | |
| SCHEMBL15022915 | 0.74 | DNM1 (0.50) | MAPTGAASMN1; SMN2MEN1APAF1 | |
| SCHEMBL11391477 | 0.72 | MAPT (0.35) | MAPTGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3855076 | 0.71 | RAD52 (0.47) | MAPTGAAKMT2AGBA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11143842 | 0.70 | KDM4E (0.46) | MAPTGAAKMT2AGBA1ALDH1A1 | |
| SCHEMBL5158945 | 0.70 | MAPT (0.51) | MAPTGAASMN1; SMN2MEN1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 539 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430876-A1 | Composition containing a direct dyestuff and a specific polymer for colouring of keratinic fibres, method for the preparation thereof and process of dyeing with such a composition | L'OREAL (FR) | 2004-06-23 | — | — | EP | claimed |
| US-20030159221-A1 | Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent | L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | claimed |
| EP-1263397-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES WITH A PARTICULAR PARAPHENYLENEDIAMINE DERIVATIVE AND A PARTICULAR DIRECT DYEING AGENT | L'OREAL (FR) | 2002-12-11 | — | — | EP | claimed |
| WO-2001066068-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES WITH A PARTICULAR PARAPHENYLENEDIAMINE DERIVATIVE AND A PARTICULAR DIRECT DYEING AGENT | L'OREAL (FR) | 2001-09-13 | — | — | WO | claimed |
| US-11896700-B2 | Process for treating keratin fibers using an anhydrous composition comprising a compound of azomethine type comprising two pyrazolopyridine units and an aqueous composition | L'OREAL (FR) | 2024-02-13 | — | — | US | disclosed |
| US-11857662-B2 | Hair coloring compositions and methods thereof | KAO USA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11696884-B2 | Compositions comprising menthol compounds as smoothing agents | SYMRISE AG (DE) | 2023-07-11 | — | — | US | disclosed |
| US-11691035-B2 | Oxidizing composition for the treatment of keratin fibers comprising at least one cationic polymer, at least one fatty amide and at least one anti-oxygen agent | L'OREAL (FR) | 2023-07-04 | — | — | US | disclosed |
| US-20230137804-A1 | PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION | L'OREAL (FR) | 2023-05-04 | — | — | US | disclosed |
| US-20230065360-A1 | COSMETIC COMPOSITION COMPRISING A POLYMER COMPRISING AT LEAST ONE CATIONIC (METH)ACRYLAMIDE UNIT, A PARTICULAR SILICONE AND AT LEAST ONE SURFACTANT | L'OREAL (FR) | 2023-03-02 | — | — | US | disclosed |
| EP-3389622-B1 | OXIDIZING COMPOSITION FOR TREATING KERATIN MATERIALS, COMPRISING A FATTY SUBSTANCE AND OXYALKYLENATED SURFACTANTS | OREAL (FR) | 2023-01-04 | — | — | EP | disclosed |
| US-11344489-B2 | Azomethine dye chromophores | BASF SE (DE) | 2022-05-31 | — | — | US | disclosed |
| US-20030159221-A1 | Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent | L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | disclosed |
| US-20030152534-A1 | Composition for dyeing keratin fibers comprising a particular aminosilicone | L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | disclosed |
| US-20030140429-A1 | Keratin fibre dyeing composition comprising a particular aminosilicone | L'OREAL S.A. (FR) | 2003-07-31 | — | — | US | disclosed |
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | L'OREAL S.A. (FR) | 2003-06-12 | — | — | US | disclosed |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2003-05-22 | — | — | US | disclosed |
| EP-1312344-A2 | Dyeing composition for keratinous fibres containing aminosilicone | L'OREAL (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-1312343-A2 | Dyeing composition for keratinous fibres containing aminosilicone | L'OREAL S.A. (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-1297819-A2 | Composition for dyeing keratinous fibres comprising a cationic azo dye | L'OREAL (FR) | 2003-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030159221-A1 | Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent | KRT18, CDC73, DAO | MAPT 1020/4885GAA 4224/4885SMN1; SMN2 4530/4885 |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | KRT18, CKAP4, KRTCAP2 | MAPT 573/4885GAA 3893/4885SMN1; SMN2 3588/4885 |
| US-20030106169-A1 | Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye | KRT18, TUBB3, TUBB1 | MAPT 468/4885GAA 4564/4885SMN1; SMN2 4216/4885 |
| US-11696884-B2 | Compositions comprising menthol compounds as smoothing agents | SMURF1, SMURF2, S1PR2 | MAPT 823/4885GAA 2704/4885SMN1; SMN2 1579/4885 |
| US-11344489-B2 | Azomethine dye chromophores | KRT18, IK, JUP | MAPT 220/4885GAA 4614/4885SMN1; SMN2 4303/4885 |
| US-11896700-B2 | Process for treating keratin fibers using an anhydrous composition comprising a compound of azomethine type comprising two pyrazolopyridine units and an aqueous composition | KRT18, DPYD, CKAP4 | MAPT 143/4885GAA 4188/4885SMN1; SMN2 3830/4885 |
| US-11857662-B2 | Hair coloring compositions and methods thereof | SPAG5, ACR, MUC1 | MAPT 944/4885GAA 2255/4885SMN1; SMN2 1764/4885 |
| US-20230065360-A1 | COSMETIC COMPOSITION COMPRISING A POLYMER COMPRISING AT LEAST ONE CATIONIC (METH)ACRYLAMIDE UNIT, A PARTICULAR SILICONE AND AT LEAST ONE SURFACTANT | KRT18, ACR, MUC1 | MAPT 804/4885GAA 2450/4885SMN1; SMN2 2197/4885 |
| US-20030152534-A1 | Composition for dyeing keratin fibers comprising a particular aminosilicone | KRT18, TUBB8, TUBA8 | MAPT 1587/4885GAA 4647/4885SMN1; SMN2 4761/4885 |
| US-20230137804-A1 | PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION | KRT18, DPYD, CKAP4 | MAPT 143/4885GAA 4188/4885SMN1; SMN2 3830/4885 |
| US-20030140429-A1 | Keratin fibre dyeing composition comprising a particular aminosilicone | KRT18, TUBB3, TUBA3E | MAPT 578/4885GAA 4193/4885SMN1; SMN2 4685/4885 |
| US-11691035-B2 | Oxidizing composition for the treatment of keratin fibers comprising at least one cationic polymer, at least one fatty amide and at least one anti-oxygen agent | KRT18, OAT, CUTA | MAPT 1187/4885GAA 3408/4885SMN1; SMN2 4607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.