Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398613 | 0.82 | MMP2 (0.44) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL10701583 | 0.82 | MMP2 (0.54) | MMP2MMP9MMP12HPGDCYP2C9 | |
| SCHEMBL11478885 | 0.81 | CYP2C9 (0.59) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11396522 | 0.78 | MMP2 (0.52) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11403527 | 0.76 | AGBL2 (0.54) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11407313 | 0.75 | AGBL2 (0.62) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11402193 | 0.75 | AGBL2 (0.76) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11475773 | 0.75 | SMN1; SMN2 (0.45) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11476701 | 0.74 | CXCL8 (0.48) | MMP2MMP9MMP12CFDF11 | |
| SCHEMBL11453265 | 0.73 | AGBL2 (0.50) | MMP2MMP9MMP12AGBL2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282245-A | ANTIINFLAMMATORY | NIPPON CHEMIPHAR CO., LTD. (JP) | 1981-08-04 | — | — | US | disclosed |