Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP12 | P39900 | 3/20 | 0.44 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11400370 | 0.84 | AKR1B1 (0.46) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11394902 | 0.82 | MMP2 (0.44) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11478885 | 0.81 | CYP2C9 (0.59) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11396522 | 0.78 | MMP2 (0.52) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11403527 | 0.76 | AGBL2 (0.54) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11407313 | 0.75 | AGBL2 (0.62) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11402193 | 0.75 | AGBL2 (0.76) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11453265 | 0.73 | AGBL2 (0.50) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL11400372 | 0.71 | MMP2 (0.38) | MMP2MMP9MMP12AGBL2HPGD | |
| SCHEMBL8163677 | 0.71 | AGBL2 (0.56) | MMP2MMP9MMP12AGBL2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282245-A | ANTIINFLAMMATORY | NIPPON CHEMIPHAR CO., LTD. (JP) | 1981-08-04 | — | — | US | disclosed |