SCHEMBL1139620

SCHEMBL1139620

[CH2]C[C@@H](O)CCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 3/20 0.49
MMP13 P45452 2/20 0.49
DPP4 P27487 1/20 0.49
MMP2 P08253 1/20 0.49
MMP9 P14780 1/20 0.49
MMP14 P50281 1/20 0.49
TDP1 Q9NUW8 1/20 0.44
ANPEP P15144 2/20 0.44
ERAP1 Q9NZ08 2/20 0.44
ERAP2 Q6P179 1/20 0.44
ACP3 P15309 1/20 0.43
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
KCNH2 Q12809 1/20 0.42
CNR2 P34972 1/20 0.42
TRPA1 O75762 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3938466 1.00 MMP12 (0.49) MMP12MMP13DPP4MMP2MMP9
SCHEMBL7285509 1.00 MMP12 (0.49) MMP12MMP13DPP4MMP2MMP9
SCHEMBL4799370 0.86 MMP2 (0.55) MMP12MMP13DPP4MMP2MMP9
SCHEMBL7294496 0.85 DPP4 (0.47) MMP12MMP13DPP4MMP2MMP9
SCHEMBL9327618 0.81 TRPA1 (0.44) SLC6A2SLC6A4SLC6A3TRPA1
SCHEMBL448011 0.80 TRPA1 (0.56) MMP12MMP13DPP4MMP2MMP9
SCHEMBL2077325 0.80 TDP1 (0.52) MMP12MMP13DPP4MMP2MMP9
SCHEMBL2074517 0.80 TDP1 (0.52) MMP12MMP13DPP4MMP2MMP9
SCHEMBL2074824 0.80 TDP1 (0.52) MMP12MMP13DPP4MMP2MMP9
SCHEMBL6692566 0.79 TAAR1 (0.43) MMP12MMP13MMP2MMP9MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1253160-B1 Electrophotographic encapsulated toner particles and method for making them CANON KK (JP) 2011-02-23 EP disclosed
US-7632618-B2 Polyhydroxyalkanoate-containing structure and manufacturing method thereof CANON KABUSHIKI KAISHA (JP) 2009-12-15 US disclosed
US-7527809-B2 Polyhydroxyalkanoate-containing magnetic structure, and manufacturing method and use thereof CANON KABUSHIKI KAISHA (JP) 2009-05-05 US disclosed
US-20090061498-A1 POLYHYDROXYALKANOATE-CONTAINING STRUCTURE AND MANUFACTURING METHOD THEREOF CANON KABUSHIKI KAISHA (JP) 2009-03-05 US disclosed
US-20090029423-A1 METHOD FOR SEPARATING TARGET COMPONENT CANON KABUSHIKI KAISHA (JP) 2009-01-29 US disclosed
EP-1254930-B1 Particles for electrophoresis, a production method thereof and a display using the particles CANON KK (JP) 2008-06-18 EP disclosed
EP-1275728-B1 Polyhydroxyalkanoate-containing structure and manufacturing method thereof CANON KK (JP) 2008-06-04 EP disclosed
US-7358070-B2 Process for formation of pattern of polyhydroxyalkanoate CANON KABUSHIKI KAISHA (JP) 2008-04-15 US disclosed
EP-1253475-B1 Electrostatic charge image developing toner, producing method therefor, and image forming method and image forming apparatus utilizing the toner CANON KK (JP) 2007-08-08 EP disclosed
US-7186459-B2 Liposome coated with polyhydroxyalkanoate and production method thereof CANON KABUSHIKI KAISHA (JP) 2007-03-06 US disclosed
US-20030206330-A1 Particles for electrophoresis, a production method thereof and a display using the articles CANON KABUSHIKI KAISHA (JP) 2003-11-06 US disclosed
US-20030203987-A1 Pigment containing ink and production method thereof CANON KABUSHIKI KAISHA (JP) 2003-10-30 US disclosed
US-20030118931-A1 Electrostatic charge image developing toner, producing method therefor, and image forming method and image forming apparatus utilizing the toner CANON KABUSHIKI KAISHA (JP) 2003-06-26 US disclosed
US-20030113368-A1 Liposome coated with polyhydroxyalkanoate and production method thereof CANON KABUSHIKI KAISHA (JP) 2003-06-19 US disclosed
US-20030104302-A1 Construct and method for making it LASALLE BANK NATIONAL ASSOCIATION 2003-06-05 US disclosed
EP-1275728-A1 Polyhydroxyalkanoate-containing structure and manufacturing method thereof CANON KABUSHIKI KAISHA (JP) 2003-01-15 EP disclosed
EP-1256606-A2 Pigment containing ink and production method thereof CANON KABUSHIKI KAISHA (JP) 2002-11-13 EP disclosed
EP-1254930-A2 Particles for electrophoresis, a production method thereof and a display using the particles CANON KABUSHIKI KAISHA (JP) 2002-11-06 EP disclosed
EP-1253160-A2 Construct and method for making it CANON KABUSHIKI KAISHA (JP) 2002-10-30 EP disclosed
EP-1253475-A2 Electrostatic charge image developing toner, producing method therefor, and image forming method and image forming apparatus utilizing the toner CANON KABUSHIKI KAISHA (JP) 2002-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030113368-A1 Liposome coated with polyhydroxyalkanoate and production method thereof LIPA, ABHD16A, LIPE MMP12 1924/4885MMP13 1623/4885DPP4 3940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.