Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11476269 | 0.81 | THRB (0.41) | — | |
| SCHEMBL11267533 | 0.78 | ALDH1A1 (0.40) | TSHRCYP2C19 | |
| SCHEMBL9500035 | 0.76 | TRIM24 (0.32) | — | |
| SCHEMBL11477389 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL11475629 | 0.74 | ALDH1A1 (0.35) | TSHRCYP2C19CYP1A2 | |
| SCHEMBL8670866 | 0.73 | CYP2C19 (0.38) | TSHRNFKB1CYP2C19CYP1A2 | |
| SCHEMBL11476206 | 0.73 | PRKCA (0.37) | TSHR | |
| SCHEMBL11206064 | 0.71 | FFAR3 (0.46) | GRIK1GRIK2CYP1A2 | |
| SCHEMBL2228829 | 0.67 | — | — | |
| SCHEMBL8749 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264500-A | Process of making 6-chloro-α-methyl-carbazole-2-acetic acid | HOFFMANN-LA ROCHE INC. (US) | 1981-04-28 | — | — | US | disclosed |