SCHEMBL1139743

SCHEMBL1139743

CC(=O)Nc1cc(S(=O)(=O)O)cc2cc(S(=O)(=O)O)c(N=Nc3ccccc3C)c(O)c12

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 8/20 0.56
▸ CYP1A2 P05177 3/20 0.56
▸ MEN1 O00255 1/20 0.56
▸ HTT P42858 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ CYP2C9 P11712 1/20 0.55
▸ MAPK1 P28482 1/20 0.55
▸ DNASE1L3 Q13609 1/20 0.55
▸ FUT8 Q9BYC5 1/20 0.54
▸ PHLPP2 Q6ZVD8 1/20 0.52
▸ PRMT1 Q99873 2/20 0.52
▸ CA2 P00918 1/20 0.48
▸ CA3 P07451 1/20 0.48
▸ PRMT3 O60678 1/20 0.46
▸ EP300 Q09472 1/20 0.46
▸ PRMT6 Q96LA8 1/20 0.46
▸ APEX1 P27695 1/20 0.44
▸ ALDH1A1 P00352 2/20 0.44
▸ HIF1A Q16665 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL110153 1.00 ENPP2 (0.56) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL185815 1.00 ENPP2 (0.56) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL185813 0.99 ENPP2 (0.55) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL27732032 0.99 ENPP2 (0.55) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL16220629 0.88 ENPP2 (0.51) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL14440807 0.88 ENPP2 (0.58) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL12954923 0.87 ENPP2 (0.68) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL10050360 0.87 ENPP2 (0.68) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL29377239 0.87 PTPN1 (0.57) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL4807909 0.87 PTPN1 (0.57) ENPP2CYP1A2MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799092-B2 Composition for simultaneously bleaching and dyeing keratin fibers, comprising at least one anionic or nonionic direct dye and at least one associative polymer L'OREAL S.A. (FR) 2010-09-21 — — US claimed
US-7736395-B2 direct dyes L'OREAL S.A. (FR) 2010-06-15 — — US claimed
EP-1738801-B1 Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid OREAL (FR) 2010-06-09 — — EP claimed
EP-1738800-B1 Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer OREAL (FR) 2010-06-09 — — EP claimed
US-20070033744-A1 Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration L'OREAL S.A. (FR) 2007-02-15 — — US claimed
US-20070033743-A1 direct dyes L'OREAL S.A. (FR) 2007-02-15 — — US claimed
EP-1738800-A1 Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer L'Oréal (FR) 2007-01-03 — — EP claimed
EP-1738801-A1 Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid L'Oréal (FR) 2007-01-03 — — EP claimed
US-20060185098-A1 Composition for bleaching and simultaneously dyeing keratin fibers, comprising 7-(6'-methylphenylazo)-1-acetamido-3,6-disulfo-8-hydroxynaphthalene L'OREAL S.A. (FR) 2006-08-24 — — US claimed
EP-1666094-A1 composition for simultaneous colouring and decolouring of keratinic fibers comprising 7-(6'-methylphenylazo)-1-acetamido-3,6-disulfo-8-hydroxynaphtalene L'OREAL (FR) 2006-06-07 — — EP claimed
EP-2387988-B1 Oxidizing composition for the treatment of keratin fibres PROCTER & GAMBLE (US) 2017-09-27 — — EP disclosed
EP-2797577-A2 COMPOSITIONS FOR DYEING KERATIN FIBERS Henkel AG & Co. KGaA (DE) 2014-11-05 — — EP disclosed
WO-2013092005-A2 COMPOSITIONS FOR DYEING KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2013-06-27 — — WO disclosed
EP-2337544-A2 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE Living Proof, Inc. (US) 2011-06-29 — — EP disclosed
EP-1697006-B2 USE OF PEPTIDES TO PROTECT SKIN FROM HAIR TREATMENT AGENTS WELLA AG (DE) 2011-02-23 — — EP disclosed
US-5972044-A Composition and method for dyeing keratin fibers WELLA AG (DE) 1999-10-26 — — US disclosed
US-5865853-A Composition for dyeing keratin fibers containing vegetable dyes, a direct dye compound and oil and method of dyeing hair using same WELLA AKTIENGESELLSCHAFT (DE) 1999-02-02 — — US disclosed
EP-0888768-A2 Hair-dye Wella Aktiengesellschaft (DE) 1999-01-07 — — EP disclosed
EP-0867170-A2 Composition and method for dyeing keratin fibres Wella Aktiengesellschaft (DE) 1998-09-30 — — EP disclosed
US-5595197-A HAIR DYE L'OREAL (FR) 1997-01-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070033744-A1 Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration KRT18, BRD7, KAT7 ENPP2 2564/4885CYP1A2 1388/4885MEN1 4300/4885
US-20070033743-A1 direct dyes KRT18, DSG1, DSP ENPP2 2513/4885CYP1A2 677/4885MEN1 4515/4885
US-20060185098-A1 Composition for bleaching and simultaneously dyeing keratin fibers, comprising 7-(6'-methylphenylazo)-1-acetamido-3,6-disulfo-8-hydroxynaphthalene KRT18, DSG1, DSP ENPP2 2986/4885CYP1A2 1983/4885MEN1 4662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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