Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.40 |
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GRK2 | P25098 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.48 |
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807909 | 1.00 | PTPN1 (0.57) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL185814 | 1.00 | PTPN1 (0.57) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL29534088 | 0.88 | ENPP2 (0.50) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL29350172 | 0.87 | ENPP2 (0.56) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL2121243 | 0.87 | ENPP2 (0.56) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL2121238 | 0.87 | ENPP2 (0.56) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL185815 | 0.87 | ENPP2 (0.56) | MEN1KMT2AENPP2FUT8HTT | |
| SCHEMBL1139743 | 0.87 | ENPP2 (0.56) | MEN1KMT2AENPP2FUT8HTT | |
| SCHEMBL110153 | 0.87 | ENPP2 (0.56) | MEN1KMT2AENPP2FUT8HTT | |
| SCHEMBL28343203 | 0.86 | USP2 (0.52) | PTPN1USP2ATML3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 696 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4701618-A1 | METHOD FOR DYEING KERATIN FIBERS, COMPRISING THE USE OF A DYE CONTAINING CHITOSANE AND A DYEING COMPOUND, AND THE USE OF A SHAMPOO | Henkel AG & Co. KGaA (DE) | 2026-03-04 | — | — | EP | claimed |
| EP-4701617-A1 | METHOD FOR DYEING KERATIN FIBERS, COMPRISING THE USE OF A DYE CONTAINING CHITOSANE AND A DYEING COMPOUND, AND THE USE OF AN AFTERTREATMENT AGENT CONTAINING PROTEIN HYDROLYSATE AND/OR AMINO ACID | Henkel AG & Co. KGaA (DE) | 2026-03-04 | — | — | EP | claimed |
| EP-3723864-B1 | THICKENED ONE-COMPONENT HAIR TONER | HENKEL AG & CO KGAA (DE) | 2026-01-14 | — | — | EP | claimed |
| EP-4452210-B1 | DYEING METHOD FOR KERATIN FIBERS COMPRISING A DIRECT AZO-DYE AND AN ORGANIC ALKALIZING AGENT, AND KIT-OF-PARTS THEREOF | KAO CORP (JP) | 2026-01-14 | — | — | EP | claimed |
| US-12383480-B2 | Dyeing method for keratin fibers comprising a direct azo-dye and an organic alkalizing agent, and kit-of-parts thereof | KAO CORPORATION (JP) | 2025-08-12 | — | — | US | claimed |
| EP-3873402-B1 | METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF AN ORGANIC SILICON COMPOUND, AN ALKALISING AGENT AND A FILM-FORMING POLYMER | HENKEL AG & CO KGAA (DE) | 2025-02-26 | — | — | EP | claimed |
| EP-3873416-B1 | METHOD FOR TREATING HAIR, COMPRISING THE APPLICATION OF A FIRST AGENT (A) HAVING A SILANE AND A CHROMOPHORIC COMPOUND, AND A SECOND AGENT (B) HAVING A FILM-FORMING POLYMER | HENKEL AG & CO KGAA (DE) | 2025-02-26 | — | — | EP | claimed |
| WO-2025036900-A1 | HAIR DYEING COMPOSITION | KAO CORPORATION (JP) | 2025-02-20 | — | — | WO | claimed |
| US-20250041181-A1 | DYEING METHOD FOR KERATIN FIBERS COMPRISING A DIRECT AZO-DYE AND AN ORGANIC ALKALIZING AGENT, AND KIT-OF-PARTS THEREOF | KAO CORPORATION (JP) | 2025-02-06 | — | — | US | claimed |
| CN-119108665-A | Electrolyte additive, aqueous electrolyte and zinc-based energy storage device | 清华大学深圳国际研究生院 | 2024-12-10 | — | — | CN | claimed |
| CN-112055604-B | Hair dye agent containing direct dye and film-forming hydrophobic polymer | 汉高股份有限及两合公司 | 2023-07-25 | — | — | CN | claimed |
| US-20230225952-A1 | ADDITIVES FOR COLORING AGENTS AND METHODS OF USE THEREOF | LIVING PROOF, INC. | 2023-07-20 | — | — | US | claimed |
| EP-4076353-A1 | TINTING CONDITIONER HAVING IMPROVED DYEING PERFORMANCE | Henkel AG & Co. KGaA (DE) | 2022-10-26 | — | — | EP | claimed |
| EP-3836893-B1 | METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, AN OLIGOALKYLSILOXANE AND A DYEING COMPOUND | HENKEL AG & CO KGAA (DE) | 2022-09-14 | — | — | EP | claimed |
| US-11382851-B2 | Hair dye composition containing at least one organic silicon compound, a direct dye and a film forming hydrophobic polymer | HENKEL AG & CO. KGAA (DE) | 2022-07-12 | — | — | US | claimed |
| US-11331258-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, an oligoalkylsiloxane and a dyeing compound | HENKEL AG & CO. KGAA (DE) | 2022-05-17 | — | — | US | claimed |
| EP-3989920-A1 | ADDITIVES FOR COLORING AGENTS AND METHODS OF USE THEREOF | Living Proof, Inc. (US) | 2022-05-04 | — | — | EP | claimed |
| CN-114292531-A | Acid dye composition and preparation method thereof | 广州恩沣新材料科技有限公司 | 2022-04-08 | — | — | CN | claimed |
| US-11291622-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, a dyeing compound and a silicon oil | HENKEL AG & CO. KGAA (DE) | 2022-04-05 | — | — | US | claimed |
| CN-114222555-A | Additives for colorants and methods of use thereof | 生活实验公司 | 2022-03-22 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11291622-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, a dyeing compound and a silicon oil | KRT18, MKI67, DSG1 | CA2 2718/4885THRB 4573/4885PTPN1 4423/4885 |
| US-11331258-B2 | Method for dyeing keratinous material, comprising the use of an organosilicon compound, an oligoalkylsiloxane and a dyeing compound | KRT18, MKI67, PCNA | CA2 1700/4885THRB 4768/4885PTPN1 4588/4885 |
| US-12383480-B2 | Dyeing method for keratin fibers comprising a direct azo-dye and an organic alkalizing agent, and kit-of-parts thereof | KRT18, PRKCH, PRKCE | CA2 268/4885THRB 1490/4885PTPN1 1116/4885 |
| US-11382851-B2 | Hair dye composition containing at least one organic silicon compound, a direct dye and a film forming hydrophobic polymer | KRT18, DSG1, CUTA | CA2 1242/4885THRB 2660/4885PTPN1 3981/4885 |
| US-20250041181-A1 | DYEING METHOD FOR KERATIN FIBERS COMPRISING A DIRECT AZO-DYE AND AN ORGANIC ALKALIZING AGENT, AND KIT-OF-PARTS THEREOF | KRT18, PRKCH, PRKCE | CA2 268/4885THRB 1490/4885PTPN1 1116/4885 |
| US-20230225952-A1 | ADDITIVES FOR COLORING AGENTS AND METHODS OF USE THEREOF | COXFA4L2, TYR, OAT | CA2 1780/4885THRB 2787/4885PTPN1 2547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.