SCHEMBL185815

SCHEMBL185815

CC(=O)Nc1cc(S(=O)(=O)O)cc2cc(S(=O)(=O)O)c(N=Nc3ccccc3C)c(O)c12.[Na].[Na]

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 8/20 0.56
▸ CYP1A2 P05177 3/20 0.56
▸ MEN1 O00255 1/20 0.56
▸ HTT P42858 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ CYP2C9 P11712 1/20 0.55
▸ MAPK1 P28482 1/20 0.55
▸ DNASE1L3 Q13609 1/20 0.55
▸ FUT8 Q9BYC5 1/20 0.54
▸ PHLPP2 Q6ZVD8 1/20 0.52
▸ PRMT1 Q99873 2/20 0.52
▸ CA2 P00918 1/20 0.48
▸ CA3 P07451 1/20 0.48
▸ PRMT3 O60678 1/20 0.46
▸ EP300 Q09472 1/20 0.46
▸ PRMT6 Q96LA8 1/20 0.46
▸ APEX1 P27695 1/20 0.44
▸ ALDH1A1 P00352 2/20 0.44
▸ HIF1A Q16665 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL110153 1.00 ENPP2 (0.56) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL1139743 1.00 ENPP2 (0.56) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL185813 0.99 ENPP2 (0.55) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL27732032 0.99 ENPP2 (0.55) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL16220629 0.88 ENPP2 (0.51) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL14440807 0.88 ENPP2 (0.58) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL12954923 0.87 ENPP2 (0.68) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL10050360 0.87 ENPP2 (0.68) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL29377239 0.87 PTPN1 (0.57) ENPP2CYP1A2MEN1HTTKMT2A
SCHEMBL4807909 0.87 PTPN1 (0.57) ENPP2CYP1A2MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2930126-B1 Fashionable aerosol dye HENKEL AG & CO KGAA (DE) 2019-10-09 — — EP claimed
US-10259946-B1 Sealing agents, methods of making and uses thereof James Hardie Technology Limited (IE) 2019-04-16 — — US disclosed
US-9173829-B2 Compositions for dyeing keratin fibers HENKEL AG & CO. KGAA (DE) 2015-11-03 — — US disclosed
US-9161898-B2 Compositions for colouring keratin fibres HENKEL AG & CO. KGAA (DE) 2015-10-20 — — US disclosed
US-20140298592-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2014-10-09 — — US disclosed
US-20140290690-A1 COMPOSITIONS FOR COLOURING KERATIN FIBRES HENKEL AG & CO. KGAA (DE) 2014-10-02 — — US disclosed
US-8632612-B2 Compositions for dyeing keratin fibers SEGETIS, INC. (US) 2014-01-21 — — US disclosed
EP-2613760-A2 COMPOSITIONS FOR DYEING KERATIN FIBERS Segetis, Inc. (US) 2013-07-17 — — EP disclosed
US-20130156716-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS SEGETIS, INC. (US) 2013-06-20 — — US disclosed
EP-2103299-B1 Oxidizing hair colourant compositions PROCTER & GAMBLE (US) 2013-02-27 — — EP disclosed
US-6485529-B1 Agent and method for coloring fibers WELLA AKTIENGESELLSCHAFT (DE) 2002-11-26 — — US disclosed
US-6461390-B1 Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same WELLA AKTIENGESELLSCHAFT (DE) 2002-10-08 — — US disclosed
US-6361571-B1 USING TAUTOMERIC NONOXIDATIVE DYES AND POLYMETHINE DYES WELLA AKTIENGESELLSCHAFT (DE) 2002-03-26 — — US disclosed
US-6231622-B1 MIXTURES; BLUE COLOR WELLA AKTIENGESELLSCHAFT (DE) 2001-05-15 — — US disclosed
US-6171347-B1 REMOVAL OF HAIR COLOR TO BE WORN FOR ONLY A SHORT PERIOD OF TIME UNDER MILD, GENTLE CONDITIONS BY USING A COMBINATION OF A SUITABLE REDUCTONE, SUCH AS ASCORBIC ACID, AND/OR A THIOL AND/OR A SULFITE WELLA AKTIENGESELLSCHAFT (DE) 2001-01-09 — — US disclosed
US-5865855-A COUPLING TWO PYRAZOLE COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 1999-02-02 — — US disclosed
US-4784959-A Method of detecting hydrocarbon fuel leaks LOCKHEED CORPORATION (US) 1988-11-15 — — US disclosed
US-4756854-A Method and apparatus for detecting hydrocarbon fuel leaks LOCKHEED CORPORATION (US) 1988-07-12 — — US disclosed
US-4745797-A Method and apparatus for detecting hydrocarbon fuel leaks LOCKHEED CORPORATION (US) 1988-05-24 — — US disclosed
US-4615828-A Method and apparatus for detecting hydrocarbon fuel leaks LOCKHEED CORPORATION (US) 1986-10-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140290690-A1 COMPOSITIONS FOR COLOURING KERATIN FIBRES KRT18, DSG1, PKN1 ENPP2 4859/4885CYP1A2 1749/4885MEN1 4097/4885
US-20140298592-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS KRT18, PKN3, IK ENPP2 4566/4885CYP1A2 3680/4885MEN1 4795/4885
US-20130156716-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS KRT18, KRTCAP2, JUP ENPP2 4770/4885CYP1A2 3762/4885MEN1 4678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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