Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL708795 | 0.95 | DNM1 (0.39) | DNM1ALDH1A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL11396945 | 0.90 | LMNA (0.39) | DNM1ALDH1A1TSHRFDPSLMNA | |
| SCHEMBL11395225 | 0.90 | DNM1 (0.42) | DNM1ALDH1A1TSHRFDPSLMNA | |
| SCHEMBL3482389 | 0.89 | — | — | |
| SCHEMBL11397907 | 0.87 | DNM1 (0.46) | DNM1ALDH1A1TSHRFDPSLMNA | |
| SCHEMBL132565 | 0.84 | LMNA (0.42) | DNM1ALDH1A1TSHRFDPSLMNA | |
| SCHEMBL3482064 | 0.84 | — | — | |
| SCHEMBL8908346 | 0.83 | TSHR (0.40) | ALDH1A1TDP1TSHR | |
| SCHEMBL3481725 | 0.77 | OPRM1 (0.39) | DNM1ALDH1A1TSHRFDPSLMNA | |
| SCHEMBL12449725 | 0.74 | DNM1 (0.36) | DNM1ALDH1A1TDP1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4296240-A | ANTI-ATHEROSCLEROTIC AGENTS | SANDOZ, INC. (US) | 1981-10-20 | — | — | US | disclosed |