Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137882 | 0.83 | TBXAS1 (0.57) | — | |
| SCHEMBL11137880 | 0.83 | TBXAS1 (0.57) | — | |
| Oxalic Acid SCHEMBL11136833 | 0.78 | TBXAS1 (0.61) | — | |
| SCHEMBL14415616 | 0.78 | CES2 (0.44) | MTNR1AMTNR1BTAAR1MAPTPTGS2 | |
| SCHEMBL11490553 | 0.78 | PTPN1 (0.42) | TAAR1MAPTPTGS2POLBMEN1 | |
| SCHEMBL11490555 | 0.78 | PTPN1 (0.42) | TAAR1MAPTPTGS2POLBMEN1 | |
| SCHEMBL9199309 | 0.77 | HTR7 (0.42) | MAPTPTGS2CES2CES1POLB | |
| SCHEMBL8553233 | 0.74 | CES2 (0.42) | PTGS2CES2CES1MAOAMAOB | |
| SCHEMBL11994159 | 0.73 | POLB (0.49) | PTGS2CES2CES1POLBGAA | |
| SCHEMBL5674623 | 0.72 | CES2 (0.41) | TAAR1PTGS2CES2CES1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028682-A2 | Intermediates useful at the preparation of compounds having anti-depressive or tranquilizing activity | Astra Läkemedel Aktiebolag (SE) | 1981-05-20 | — | — | EP | disclosed |