Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | BAD | Q92934 | 1/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10967132 | 0.92 | PTGS2 (0.44) | NPC1RAB9APTGS2TBXAS1 | |
| SCHEMBL8675717 | 0.85 | TBXAS1 (0.41) | CES2CES1MAOAMAOBPTPN1 | |
| SCHEMBL27629299 | 0.80 | MAOB (0.41) | CES2CES1MAOAMAOBPTPN1 | |
| SCHEMBL9377885 | 0.79 | PTPN1 (0.48) | CES2CES1MAOAMAOBPTPN1 | |
| SCHEMBL5674623 | 0.79 | CES2 (0.41) | CES2CES1MAOAMAOBPTPN1 | |
| SCHEMBL9199309 | 0.79 | HTR7 (0.42) | CES2CES1PTPN1NPC1RAB9A | |
| SCHEMBL5268885 | 0.78 | MTNR1A (0.47) | TBXAS1 | |
| SCHEMBL4285163 | 0.76 | CES2 (0.48) | CES2CES1PTPN1NPC1RAB9A | |
| SCHEMBL7413792 | 0.76 | PTPN1 (0.45) | CES2CES1MAOAMAOBPTPN1 | |
| SCHEMBL11994159 | 0.76 | POLB (0.49) | CES2CES1PTPN1PTGS2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816362-A1 | THIAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1998-01-07 | — | — | EP | disclosed |