Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489613 | 1.00 | SIGMAR1 (0.51) | SIGMAR1EBPPKMMAPK1ADORA3 | |
| SCHEMBL13863944 | 0.88 | ADORA3 (0.52) | SIGMAR1EBPPKMMAPK1ADORA3 | |
| SCHEMBL11471354 | 0.88 | ADORA3 (0.52) | SIGMAR1EBPPKMMAPK1ADORA3 | |
| SCHEMBL11493711 | 0.85 | USP2 (0.39) | SIGMAR1SMN1; SMN2USP2ALOX15TSHR | |
| SCHEMBL11250417 | 0.83 | PKM (0.56) | PKMMAPK1SMN1; SMN2USP2ALOX15 | |
| SCHEMBL11487234 | 0.79 | KDM4E (0.41) | SIGMAR1SMN1; SMN2USP2ALOX15TSHR | |
| SCHEMBL11489440 | 0.78 | KDM4E (0.50) | ALDH1A1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL11486129 | 0.77 | SMN1; SMN2 (0.48) | SIGMAR1SMN1; SMN2USP2ALOX15TSHR | |
| SCHEMBL11486124 | 0.77 | SMN1; SMN2 (0.48) | SIGMAR1SMN1; SMN2USP2ALOX15TSHR | |
| SCHEMBL11492558 | 0.77 | SIGMAR1 (0.52) | SIGMAR1EBPMAPK1ADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283534-A | Reductive alkylation of nitrogen heterocycles | BASF AKTIENGESELLSCHAFT (DE) | 1981-08-11 | — | — | US | disclosed |