Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810870 | 0.85 | MEN1 (0.52) | PKMMAPK1SMN1; SMN2USP2ALOX15 | |
| SCHEMBL9810871 | 0.85 | MEN1 (0.52) | PKMMAPK1SMN1; SMN2USP2ALOX15 | |
| SCHEMBL11399593 | 0.83 | SIGMAR1 (0.51) | PKMMAPK1SMN1; SMN2USP2ALOX15 | |
| SCHEMBL11489613 | 0.83 | SIGMAR1 (0.51) | PKMMAPK1SMN1; SMN2USP2ALOX15 | |
| SCHEMBL11471354 | 0.80 | ADORA3 (0.52) | PKMMAPK1SMN1; SMN2USP2ALOX15 | |
| SCHEMBL13863944 | 0.80 | ADORA3 (0.52) | PKMMAPK1SMN1; SMN2USP2ALOX15 | |
| SCHEMBL13499548 | 0.77 | ALDH1A1 (0.73) | SMN1; SMN2USP2ALOX15TSHRKDM4E | |
| SCHEMBL3574805 | 0.76 | TSHR (0.71) | SMN1; SMN2USP2ALOX15TSHRKDM4E | |
| SCHEMBL3574801 | 0.76 | TSHR (0.71) | SMN1; SMN2USP2ALOX15TSHRKDM4E | |
| SCHEMBL13539640 | 0.73 | TSHR (0.72) | SMN1; SMN2USP2ALOX15TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017893-B1 | PROCESS FOR THE PREPARATION OF HETEROCYCLIC TERTIARY ARALKYL AMINES | BASF Aktiengesellschaft (DE) | 1982-03-24 | — | — | EP | disclosed |
| US-4283534-A | Reductive alkylation of nitrogen heterocycles | BASF AKTIENGESELLSCHAFT (DE) | 1981-08-11 | — | — | US | disclosed |
| EP-0017893-A1 | Process for the preparation of heterocyclic tertiary aralkyl amines | BASF Aktiengesellschaft (DE) | 1980-10-29 | — | — | EP | disclosed |