Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390266 | 0.81 | TAS1R3 (0.38) | HTTLMNASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL11402318 | 0.80 | TAS1R3 (0.43) | HTTLMNASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL11399777 | 0.77 | LMNA (0.48) | DRD2LMNAALDH1A1RAB9AKDM4E | |
| SCHEMBL8527632 | 0.77 | HTT (0.42) | HTTDRD2SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL11396949 | 0.76 | ALDH1A1 (0.38) | HTTLMNASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL11399056 | 0.76 | ALDH1A1 (0.38) | HTTLMNASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL25514824 | 0.73 | ALDH1A1 (0.44) | HTTLMNASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL7053647 | 0.73 | PKM (0.51) | HTTTP53ALDH1A1PKMMAPT | |
| SCHEMBL11800671 | 0.72 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL10476844 | 0.72 | PDE5A (0.45) | LMNATP53ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4301159-A | FOR GASTRIC DISORDERS, ANTIEMETICS | SHIONOGI & CO., LTD. (JP) | 1981-11-17 | — | — | US | disclosed |