Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11387848 | 0.89 | L3MBTL1 (0.36) | HSD11B1HTR6CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL2285511 | 0.80 | HTR6 (0.58) | HTR6CA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL5482437 | 0.79 | HTR6 (0.61) | HSD11B1HTR6CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL11400136 | 0.76 | MEN1 (0.44) | ALDH1A1HSD17B10SMN1; SMN2CYP2C9HPGD | |
| SCHEMBL372641 | 0.74 | CYP2E1 (0.44) | HSD11B1HTR6CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL9628488 | 0.72 | — | — | |
| SCHEMBL1322510 | 0.72 | — | — | |
| SCHEMBL3272540 | 0.71 | HTR6 (0.39) | HSD11B1HTR6ALDH1A1TSHRCYP2C9 | |
| SCHEMBL13803806 | 0.69 | KEAP1 (0.62) | CA1CA2ALDH1A1CA12CA9 | |
| SCHEMBL11395620 | 0.68 | MEN1 (0.47) | HTR6ALDH1A1SMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294838-A | ANTIBRONCHOSPASMOLYTIC AGENTS | WARNER-LAMBERT COMPANY, A CORP. OF DE | 1981-10-13 | — | — | US | disclosed |