Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399693 | 0.76 | HCAR1 (0.43) | PDE3APDE3BLMNAHPGDHRH3 | |
| SCHEMBL12362749 | 0.69 | ALDH1A1 (0.37) | PAK1SLC5A1SLC5A2MEN1ESR1 | |
| SCHEMBL27574380 | 0.69 | NSD2 (0.51) | LMNACYP1A2POLBMAPTHPGD | |
| SCHEMBL31196427 | 0.69 | CYP11B2 (0.43) | PAK1LMNAEGFRLCKPOLB | |
| SCHEMBL17664675 | 0.68 | RGS4 (0.47) | LMNAMEN1NPC1CYP1A2ADORA3 | |
| SCHEMBL11390024 | 0.68 | HSP90AA1 (0.41) | LMNAMEN1HSP90AA1SLC6A2SLC6A4 | |
| SCHEMBL11389561 | 0.67 | PAK1 (0.31) | PAK1MAPT | |
| SCHEMBL11401372 | 0.67 | PDE3B (0.40) | PAK1PDE3APDE3BCYP3A4HPGD | |
| SCHEMBL22349820 | 0.67 | GSK3A (0.44) | MEN1NPC1POLBHPGDALOX15 | |
| SCHEMBL12362740 | 0.67 | TDP1 (0.41) | LMNAMEN1NPC1ESR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279637-A | Herbicidal N-substituted 4-imidazolin-2-ones | VELSICOL CHEMICAL CORPORATION (US) | 1981-07-21 | — | — | US | disclosed |