Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | CTRC | Q99895 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.32 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399693 | 0.79 | HCAR1 (0.43) | PDE3BPDE3AHPGDKDM4EALDH1A1 | |
| SCHEMBL7133435 | 0.70 | GSK3A (0.48) | HPGDKDM4EALDH1A1SLC9A3SMN1; SMN2 | |
| SCHEMBL11545651 | 0.68 | PDE3B (0.52) | PDE3BPDE3AHPGDKDM4EALDH1A1 | |
| SCHEMBL11402098 | 0.67 | PAK1 (0.36) | PDE3BPDE3AHPGDCYP3A4PAK1 | |
| SCHEMBL11831603 | 0.66 | PDE3B (0.40) | PDE3BPDE3ACTRCHPGDKDM4E | |
| SCHEMBL30931108 | 0.66 | ALOX5 (0.42) | HPGDKDM4EALDH1A1SLC9A3SMN1; SMN2 | |
| SCHEMBL6081579 | 0.65 | HSP90AA1 (0.45) | HPGDCYP3A4 | |
| SCHEMBL3821433 | 0.65 | HTR2A (0.56) | CTRCHPGDCYP3A4NR1H2SMN1; SMN2 | |
| SCHEMBL11388402 | 0.64 | MGLL (0.49) | SLC9A3 | |
| SCHEMBL31196427 | 0.63 | CYP11B2 (0.43) | RXFP1PAK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279637-A | Herbicidal N-substituted 4-imidazolin-2-ones | VELSICOL CHEMICAL CORPORATION (US) | 1981-07-21 | — | — | US | disclosed |