Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12498992 | 0.74 | NOS3 (0.48) | MAPTNOS3NOS1NOS2KMT2A | |
| SCHEMBL10862753 | 0.71 | MAPT (0.38) | MAPTKMT2AGAAMEN1SMN1; SMN2 | |
| SCHEMBL22119463 | 0.71 | NOS2 (0.45) | MAPTNOS3NOS1NOS2GAA | |
| SCHEMBL12411157 | 0.69 | HRH4 (0.51) | NOS3NOS1NOS2KMT2AGAA | |
| SCHEMBL23025113 | 0.69 | KMT2A (0.73) | NOS3NOS1NOS2KMT2AGAA | |
| SCHEMBL14946746 | 0.69 | RAB9A (0.51) | MAPTKMT2AGAAMAPK1MEN1 | |
| SCHEMBL12883321 | 0.69 | MAPT (0.59) | MAPTKMT2AGAAMAPK1MEN1 | |
| SCHEMBL11403184 | 0.68 | LMNA (0.47) | MAPTNOS3NOS1NOS2KMT2A | |
| SCHEMBL11432228 | 0.67 | MAPT (0.34) | MAPTSMN1; SMN2LMNA | |
| SCHEMBL14842309 | 0.67 | NOS2 (0.50) | MAPTNOS3NOS1NOS2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032625-A2 | Water-soluble monoazo dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-07-29 | — | — | EP | disclosed |