Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620437 | 0.80 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2HPGDMAPK1MAPT | |
| SCHEMBL11067069 | 0.78 | PDE7A (0.45) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL5695838 | 0.76 | LTA4H (0.43) | ALDH1A1SMN1; SMN2L3MBTL1ATMHPGD | |
| SCHEMBL8729226 | 0.75 | ALDH1A1 (0.62) | ALDH1A1LMNASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL457863 | 0.75 | HSPB1 (0.68) | ALDH1A1LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL268150 | 0.75 | MEN1 (0.68) | ALDH1A1LMNASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL28760493 | 0.75 | HTT (0.55) | ALDH1A1LMNASMN1; SMN2HTTCRHBP | |
| SCHEMBL9000963 | 0.74 | MEN1 (0.42) | ALDH1A1LMNASMN1; SMN2HTTL3MBTL1 | |
| Hydrogen Sulfide SCHEMBL27890271 | 0.74 | LTA4H (0.41) | ALDH1A1SMN1; SMN2L3MBTL1ATMHPGD | |
| SCHEMBL11067104 | 0.74 | HSPB1 (0.43) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021215-A1 | Pseudotrisaccharides, their preparation and use as medicaments | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |