Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26325448 | 0.86 | TSHR (0.48) | CRHR1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL31285548 | 0.86 | TSHR (0.48) | CRHR1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL11423946 | 0.86 | SMN1; SMN2 (0.53) | CRHR1SMN1; SMN2HTR3EHTR3BHTR3A | |
| SCHEMBL11416362 | 0.84 | HTR3E (0.51) | CRHR1SMN1; SMN2HTR3EHTR3BHTR3A | |
| SCHEMBL11404995 | 0.83 | RAB9A (0.46) | SMN1; SMN2POLBMEN1KMT2AMAPT | |
| SCHEMBL10966244 | 0.78 | TSHR (0.41) | CRHR1SMN1; SMN2HTR3EHTR3BHTR3A | |
| SCHEMBL28524112 | 0.76 | CES2 (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL26325451 | 0.76 | CES2 (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9019938 | 0.74 | HDAC8 (0.49) | SMN1; SMN2POLBMEN1KMT2AKCNK3 | |
| SCHEMBL11404997 | 0.74 | TSHR (0.43) | SMN1; SMN2ESR1ESR2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230727-A | N-BENZYLIDENEANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4187317-A | Sunscreen and erythema treating with N-benzylidene anilenes | WILLIAM H. RORER, INC. (US) | 1980-02-05 | — | — | US | disclosed |