SCHEMBL11413405

SCHEMBL11413405

O=c1[nH]nc(CN2CCOCC2)c2ccccc12

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PARP1 P09874 13/20 0.70
▸ PRMT5 O14744 1/20 0.53
▸ MEN1 O00255 2/20 0.51
▸ ALDH1A1 P00352 2/20 0.51
▸ KMT2A Q03164 2/20 0.51
▸ AR P10275 2/20 0.50
▸ LMNA P02545 1/20 0.49
▸ POLB P06746 1/20 0.49
▸ KDM4E B2RXH2 1/20 0.46
▸ GAA P10253 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ THRB P10828 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ RECQL P46063 1/20 0.46
▸ BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5160196 0.84 LMNA (0.57) PARP1PRMT5ALDH1A1KMT2AAR
SCHEMBL13721430 0.75 PARP1 (0.53) PARP1MEN1ALDH1A1KMT2ALMNA
SCHEMBL6328650 0.74 PARP1 (0.57) PARP1KMT2A
SCHEMBL6324300 0.72 PARP1 (0.60) PARP1PRMT5
SCHEMBL1720304 0.72 PARP1 (0.53) PARP1MEN1ALDH1A1KMT2AKDM4E
SCHEMBL23099038 0.72 PRMT5 (0.73) PARP1PRMT5ARLMNAPOLB
SCHEMBL12955691 0.71 PARP1 (0.58) PARP1AR
SCHEMBL60751 0.71 PARP1 (0.53) PARP1
SCHEMBL1719771 0.70 ALDH1A1 (0.62) PARP1MEN1ALDH1A1KMT2AKDM4E
SCHEMBL28875476 0.70 JAK2 (0.49) PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 — — US claimed
US-4237215-A DECOMPOSING N-HALO COMPOUND IN PRESENCE OF ORGANIC SILVER SALT TO PRODUCE SILVER HALIDE FUJI PHOTO FILM CO., LTD. (JP) 1980-12-02 — — US disclosed
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 — — US disclosed
US-4144072-A CONTAINING A PHTHALAZINONE AND A PHTHALIMIDE FUJI PHOTO FILM CO., LTD. (JP) 1979-03-13 — — US disclosed
US-4125403-A ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, PHTHALAZINONE, AND A BENZOXAZINEDIONE OR QUINAZOLINEDIONE FUJI PHOTO FILM CO., LTD. 1978-11-14 — — US disclosed
US-4076534-A Heat developable light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 — — US disclosed
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