Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GPR27 | Q9NS67 | 5/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432038 | 0.94 | CASP6 (0.40) | CASP6CTDSP1TIMP3HPSEENPP2 | |
| SCHEMBL11402861 | 0.89 | ALDH1A1 (0.40) | CASP6HPSEMEN1KMT2AMAPT | |
| SCHEMBL11407773 | 0.88 | TIMP3 (0.52) | CASP6CTDSP1TIMP3HPSEENPP2 | |
| SCHEMBL11412516 | 0.87 | NT5E (0.42) | CASP6ENPP2MEN1KMT2AMAPT | |
| SCHEMBL11432048 | 0.87 | CASP6 (0.40) | CASP6CTDSP1TIMP3HPSEENPP2 | |
| SCHEMBL11416598 | 0.87 | CASP6 (0.41) | CASP6CTDSP1TIMP3HPSEENPP2 | |
| SCHEMBL11513047 | 0.85 | APEX1 (0.45) | CASP6CTDSP1TIMP3HPSEENPP2 | |
| SCHEMBL11468128 | 0.83 | TIMP3 (0.50) | CASP6CTDSP1TIMP3HPSEENPP2 | |
| SCHEMBL11440315 | 0.83 | POLB (0.41) | CASP6TIMP3HPSEMEN1KMT2A | |
| SCHEMBL11437291 | 0.82 | MAPT (0.44) | MEN1KMT2AMAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | claimed |
| US-4231958-A | AMINOPHENYLENECARBONYL /AND SULFONYL/IMINONAPHTHALENE INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1980-11-04 | — | — | US | disclosed |
| US-4229370-A | INHIBITORS OF THE COMPLEMENT SYSTEM, IMMUNOLOGY | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4155930-A | Ureylene phenylene anionic naphthalenesulfonic acids | AMERICAN CYANAMID COMPANY (US) | 1979-05-22 | — | — | US | disclosed |