Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.41 |
| ▸ | WEE1 | P30291 | 3/20 | 0.41 |
| ▸ | CDK4 | P11802 | 4/20 | 0.39 |
| ▸ | CCND1 | P24385 | 4/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.39 |
| ▸ | PRKCA | P17252 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533447 | 0.81 | WEE1 (0.37) | CES1CHEK1WEE1CDK4CCND1 | |
| SCHEMBL11668896 | 0.80 | CES1 (0.42) | CES1CHEK1WEE1CDK4CCND1 | |
| SCHEMBL11531116 | 0.78 | CHEK1 (0.35) | CES1CHEK1WEE1CDK4CCND1 | |
| SCHEMBL11756770 | 0.77 | PARP1 (0.45) | CES1CHEK1WEE1CDK4CCND1 | |
| SCHEMBL11765410 | 0.76 | WEE1 (0.42) | CES1CHEK1WEE1CDK5CDK5R1 | |
| SCHEMBL10396142 | 0.76 | TGM2 (0.36) | CHEK1WEE1PRKCAEGFRPBRM1 | |
| SCHEMBL11535554 | 0.75 | GSK3B (0.37) | CHEK1WEE1CDK4CCND1GSK3B | |
| SCHEMBL11430142 | 0.73 | CYP1A2 (0.43) | CES1CHEK1WEE1CDK4CCND1 | |
| SCHEMBL261439 | 0.71 | GSK3B (0.52) | CES1CHEK1WEE1GSK3BRET | |
| SCHEMBL2142727 | 0.71 | PARP1 (0.39) | CES1CHEK1WEE1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181530-A | ELECTRON ATTRACTING PHTHALIMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-01-01 | — | — | US | claimed |
| US-4181530-A | ELECTRON ATTRACTING PHTHALIMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-01-01 | — | — | US | disclosed |