Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.36 |
| ▸ | WEE1 | P30291 | 11/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 10/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11420985 | 0.76 | CES1 (0.44) | TGM2WEE1CHEK1EGFRPRKCA | |
| SCHEMBL11713698 | 0.73 | KDR (0.39) | KDM4EALDH1A1HPGDMAPKAPK2JAK3 | |
| SCHEMBL11533447 | 0.71 | WEE1 (0.37) | WEE1CHEK1EGFRPRKCAKDM4E | |
| SCHEMBL10396748 | 0.70 | KDM4E (0.39) | TGM2WEE1CHEK1PRKCAKDM4E | |
| SCHEMBL11765410 | 0.70 | WEE1 (0.42) | WEE1CHEK1EGFRPRKCAJAK3 | |
| SCHEMBL11531116 | 0.68 | CHEK1 (0.35) | WEE1CHEK1PRKCAKDM4EGAA | |
| SCHEMBL10396744 | 0.67 | ALDH1A1 (0.35) | PRKCAKDM4EALDH1A1GAAHPGD | |
| SCHEMBL10396143 | 0.67 | PKM (0.36) | WEE1CHEK1PRKCAKDM4EALDH1A1 | |
| SCHEMBL11535554 | 0.66 | GSK3B (0.37) | WEE1CHEK1KDM4EALDH1A1GAA | |
| SCHEMBL11756770 | 0.65 | PARP1 (0.45) | WEE1CHEK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4919848-A | Process for the quenching of fluorescence, and new cationic naphthalene-peri-dicarboxylic acid imide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-04-24 | — | — | US | disclosed |