Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 12/20 | 0.35 |
| ▸ | WEE1 | P30291 | 12/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531116 | 0.83 | CHEK1 (0.35) | GSK3BCDK4CCND1KDM4EGAA | |
| SCHEMBL11533447 | 0.81 | WEE1 (0.37) | GSK3BCDK4CCND1KDM4EGAA | |
| SCHEMBL11529207 | 0.75 | GSK3B (0.42) | GSK3BCDK4CCND1KDM4EGAA | |
| SCHEMBL11420985 | 0.75 | CES1 (0.44) | GSK3BCDK4CCND1MAPTCHEK1 | |
| SCHEMBL11765410 | 0.66 | WEE1 (0.42) | GSK3BCHEK1WEE1LCK | |
| SCHEMBL10396142 | 0.66 | TGM2 (0.36) | KDM4EGAACHEK1WEE1ALDH1A1 | |
| SCHEMBL11756770 | 0.65 | PARP1 (0.45) | GSK3BCDK4CCND1MAPTCHEK1 | |
| SCHEMBL3633834 | 0.63 | ALDH1A1 (0.42) | KDM4EGAAMAPTCYP1A2CYP2D6 | |
| SCHEMBL11668896 | 0.61 | CES1 (0.42) | GSK3BCDK4CCND1MAPTCHEK1 | |
| SCHEMBL11430142 | 0.61 | CYP1A2 (0.43) | GSK3BCDK4CCND1CHEK1WEE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139532-A | OPTICAL BRIGHTENERS FOR POLYESTERS AND THEIR BLENDS WITH COTTON | BASF AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | disclosed |