Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 7/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.35 |
| ▸ | STK10 | O94804 | 2/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.33 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531116 | 0.85 | CHEK1 (0.35) | WEE1CHEK1CES1GSK3BPRKCA | |
| SCHEMBL11535554 | 0.81 | GSK3B (0.37) | WEE1CHEK1GSK3BSTK10SLK | |
| SCHEMBL11420985 | 0.81 | CES1 (0.44) | WEE1CHEK1CES1GSK3BPRKCA | |
| SCHEMBL11756770 | 0.73 | PARP1 (0.45) | WEE1CHEK1CES1GSK3BSTK10 | |
| SCHEMBL11765410 | 0.72 | WEE1 (0.42) | WEE1CHEK1CES1GSK3BPRKCA | |
| SCHEMBL10396142 | 0.71 | TGM2 (0.36) | WEE1CHEK1PRKCAEGFRPBRM1 | |
| SCHEMBL11530530 | 0.70 | KDR (0.44) | WEE1CHEK1GSK3BSTK10SLK | |
| SCHEMBL11717398 | 0.67 | HPGD (0.41) | GSK3BCDK4CCND1GSK3ACDK5 | |
| SCHEMBL11717134 | 0.67 | KDM4E (0.43) | GSK3BPRKCASTK10SLKCDK4 | |
| SCHEMBL11430142 | 0.66 | CYP1A2 (0.43) | WEE1CHEK1CES1GSK3BPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139532-A | OPTICAL BRIGHTENERS FOR POLYESTERS AND THEIR BLENDS WITH COTTON | BASF AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | disclosed |