Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.39 |
| ▸ | CES1 | P23141 | 4/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573319 | 0.95 | LMNA (0.56) | LMNATSHRPOLBALDH1A1KDM4E | |
| SCHEMBL7243740 | 0.74 | PTPN1 (0.49) | LMNATSHRPOLBALDH1A1KDM4E | |
| SCHEMBL3782935 | 0.72 | PTPN1 (0.51) | LMNATSHRPOLBALDH1A1KDM4E | |
| SCHEMBL21197441 | 0.69 | TSHR (0.53) | LMNATSHRPOLBALDH1A1KDM4E | |
| SCHEMBL28927137 | 0.68 | LMNA (0.54) | LMNATSHRPOLBALDH1A1KDM4E | |
| SCHEMBL5317428 | 0.67 | ALDH1A1 (0.54) | LMNATSHRPOLBALDH1A1MAPT | |
| SCHEMBL9844628 | 0.67 | TSHR (0.50) | LMNATSHRPOLBALDH1A1KDM4E | |
| SCHEMBL30246161 | 0.64 | LMNA (0.55) | LMNATSHRPOLBALDH1A1KDM4E | |
| SCHEMBL20826897 | 0.63 | KDM4E (0.50) | LMNATSHRPOLBALDH1A1KDM4E | |
| SCHEMBL6141447 | 0.62 | CES2 (0.50) | TSHRALDH1A1HSD17B10CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9474270-B2 | Methods and compositions for controlling pests | Bioprosepect Limited (AU) | 2016-10-25 | — | — | US | disclosed |
| US-20140336269-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING PESTS | UNIVERSITY OF WESTERN SYDNEY (AU) | 2014-11-13 | — | — | US | disclosed |
| US-20120184625-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING PESTS | UNIVERSITY OF WESTERN SYDNEY (AU) | 2012-07-19 | — | — | US | disclosed |
| EP-1392119-B1 | METHODS AND COMPOSITIONS FOR CONTROLLING PESTS | BIO GENE TECHNOLOGY LTD (AU) | 2011-04-13 | — | — | EP | disclosed |
| US-7820209-B2 | Using compositions comprising as active ingredients beta-diones, particularly beta-diketones and beta-triketones, from volatile oil-bearing plants; for preventing, eradicating, repelling or mitigating harmful or undesired pests including insects, arachnids, helminths. molluscs, protozoa, and viruses | BIOPROSPECT LIMITED (AU) | 2010-10-26 | — | — | US | disclosed |
| US-20100227009-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING PESTS | BIOPROSPECT LIMITED (AU) | 2010-09-09 | — | — | US | disclosed |
| US-20080234386-A1 | Using compositions comprising as active ingredients beta-diones, particularly beta-diketones and beta-triketones, from volatile oil-bearing plants; for preventing, eradicating, repelling or mitigating harmful or undesired pests including insects, arachnids, helminths. molluscs, protozoa, and viruses | BIOPROSPECT LIMITED (AU) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184625-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING PESTS | CYP51A1, MAVS, JUP | LMNA 32/4885TSHR 4763/4885POLB 2369/4885 |
| US-20140336269-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING PESTS | CYP51A1, MAVS, JUP | LMNA 32/4885TSHR 4763/4885POLB 2369/4885 |
| US-20080234386-A1 | Using compositions comprising as active ingredients beta-diones, particularly beta-diketones and beta-triketones, from volatile oil-bearing plants; for preventing, eradicating, repelling or mitigating harmful or undesired pests including insects, arachnids, helminths. molluscs, protozoa, and viruses | DLK1, CYP51A1, TPSD1 | LMNA 162/4885TSHR 4758/4885POLB 1984/4885 |
| US-20100227009-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING PESTS | CYP51A1, MAVS, JUP | LMNA 32/4885TSHR 4763/4885POLB 2369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.