Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.56 |
| ▸ | HTR6 | P50406 | 7/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7450769 | 0.99 | CHRM3 (0.55) | CHRM3HTR6CHRM2CHRM1DRD2 | |
| SCHEMBL7407559 | 0.85 | CHRM3 (0.47) | CHRM3HTR6CHRM2CHRM1DRD2 | |
| Hydrochloric Acid SCHEMBL7408916 | 0.84 | CHRM3 (0.46) | CHRM3HTR6CHRM2CHRM1DRD2 | |
| SCHEMBL7412311 | 0.77 | HTR6 (0.61) | HTR6CYP1A2CYP2D6 | |
| SCHEMBL7410885 | 0.75 | HTR6 (0.43) | CHRM3HTR6CHRM2CHRM1DRD2 | |
| Hydrochloric Acid SCHEMBL7413056 | 0.74 | HTR6 (0.42) | CHRM3HTR6CHRM2CHRM1DRD2 | |
| SCHEMBL11421176 | 0.73 | DRD2 (0.50) | CHRM3HTR6DRD2DRD1DRD3 | |
| SCHEMBL8891132 | 0.72 | CHRM3 (1.00) | CHRM3CHRM2CHRM1DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL7407796 | 0.72 | DRD2 (0.49) | CHRM3HTR6DRD2DRD3 | |
| SCHEMBL7409136 | 0.71 | HTR6 (0.38) | CHRM3HTR6CHRM2CHRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224335-A | INOTROPIC AGENTS USED FOR TREATING CONGESTIVE HEART FAILURE IN MAMMALS | STERLING DRUG INC. (US) | 1980-09-23 | — | — | US | claimed |
| US-4224335-A | INOTROPIC AGENTS USED FOR TREATING CONGESTIVE HEART FAILURE IN MAMMALS | STERLING DRUG INC. (US) | 1980-09-23 | — | — | US | disclosed |