Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7411937 | 0.99 | HTR6 (0.37) | HTR6CHRM3DRD2DRD1CHRM2 | |
| SCHEMBL7407559 | 0.81 | CHRM3 (0.47) | HTR6CHRM3DRD2CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7408916 | 0.80 | CHRM3 (0.46) | HTR6CHRM3DRD2CHRM2CHRM1 | |
| SCHEMBL11423799 | 0.71 | CHRM3 (0.56) | HTR6CHRM3DRD2DRD1CHRM2 | |
| SCHEMBL11421176 | 0.71 | DRD2 (0.50) | HTR6CHRM3DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL7450769 | 0.70 | CHRM3 (0.55) | HTR6CHRM3DRD2DRD1CHRM2 | |
| Hydrochloric Acid SCHEMBL7407796 | 0.70 | DRD2 (0.49) | HTR6CHRM3DRD2 | |
| SCHEMBL7412311 | 0.70 | HTR6 (0.61) | HTR6 | |
| SCHEMBL4790752 | 0.70 | MCHR1 (0.41) | — | |
| SCHEMBL7413544 | 0.69 | HTR1F (0.41) | CHRM3DRD2DRD1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |