Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 10/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | HTR7 | P34969 | 4/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7408916 | 0.99 | CHRM3 (0.46) | CHRM3HTR6CHRM2CHRM1HTR1A | |
| SCHEMBL11423799 | 0.85 | CHRM3 (0.56) | CHRM3HTR6CHRM2CHRM1HTR1A | |
| Hydrochloric Acid SCHEMBL7450769 | 0.84 | CHRM3 (0.55) | CHRM3HTR6CHRM2CHRM1HTR1A | |
| SCHEMBL7409136 | 0.81 | HTR6 (0.38) | CHRM3HTR6CHRM2CHRM1DRD2 | |
| Hydrochloric Acid SCHEMBL7411937 | 0.80 | HTR6 (0.37) | CHRM3HTR6CHRM2CHRM1DRD2 | |
| SCHEMBL7412311 | 0.78 | HTR6 (0.61) | HTR6 | |
| SCHEMBL7410885 | 0.76 | HTR6 (0.43) | CHRM3HTR6CHRM2CHRM1HTR3A | |
| Hydrochloric Acid SCHEMBL7413056 | 0.75 | HTR6 (0.42) | CHRM3HTR6CHRM2CHRM1HTR3A | |
| SCHEMBL11421176 | 0.71 | DRD2 (0.50) | CHRM3HTR6DRD2DRD4DRD3 | |
| SCHEMBL14591308 | 0.71 | CHRM3 (0.69) | CHRM3CHRM2CHRM1HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000651-A2 | FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-01-03 | — | — | WO | disclosed |
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |