Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | GLA | P06280 | 4/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 4/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA3 | P07451 | 2/20 | 0.57 |
| ▸ | CA4 | P22748 | 2/20 | 0.57 |
| ▸ | CA6 | P23280 | 2/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11402546 | 0.89 | SLC16A3 (0.61) | SLC16A3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11396698 | 0.89 | ALDH1A1 (0.78) | SLC16A3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11395960 | 0.84 | ALDH1A1 (0.61) | SLC16A3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11423923 | 0.81 | SLC16A3 (0.57) | SLC16A3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4037662 | 0.80 | NPC1 (0.60) | SLC16A3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30488625 | 0.79 | GLA (0.62) | SLC16A3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11402397 | 0.78 | MAPT (0.67) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL203997 | 0.78 | SLC16A3 (1.00) | SLC16A3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11397132 | 0.78 | MAPT (0.70) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL10305766 | 0.77 | ALDH1A1 (0.63) | SLC16A3ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130288268-A1 | SULFENIC ACID-REACTIVE COMPOUNDS AND THEIR METHODS OF SYNTHESIS AND USE IN DETECTION OR ISOLATION OF SULFENIC ACID-CONTAINING COMPOUNDS | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2013-10-31 | — | — | US | claimed |
| US-7803630-B2 | Method for detecting target compounds containing sulfenic acids using new reagents | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2010-09-28 | — | — | US | claimed |
| US-20080070261-A1 | SULFENIC ACID-REACTIVE COMPOUNDS | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2008-03-20 | — | — | US | claimed |
| US-7294748-B2 | Sulfenic acid-reactive compounds and their methods of synthesis | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2007-11-13 | — | — | US | claimed |
| WO-2006044364-A2 | SULFENIC ACID-REACTIVE COMPOUNDS AND THEIR METHODS OF SYNTHESIS AND USE IN DETECTION OR ISOLATION OF SULFENIC ACID-CONTAINING COMPOUNDS | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2006-04-27 | — | — | WO | claimed |
| US-20060084173-A1 | Sulfenic acid-reactive compounds and their methods of synthesis and use in detection or isolation of sulfenic acid-containing compounds | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2006-04-20 | — | — | US | claimed |
| US-8841132-B2 | Method for detecting compounds containing sulfenic acid using a 1,3-cyclohexanedione-based probe | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2014-09-23 | — | — | US | disclosed |
| US-20130288268-A1 | SULFENIC ACID-REACTIVE COMPOUNDS AND THEIR METHODS OF SYNTHESIS AND USE IN DETECTION OR ISOLATION OF SULFENIC ACID-CONTAINING COMPOUNDS | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2013-10-31 | — | — | US | disclosed |
| US-8486642-B2 | Method of synthesizing 1,3-cyclohexadione derived reagents useful for detection or isolation of sulfenic acid-containing compounds | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2013-07-16 | — | — | US | disclosed |
| US-20100317027-A1 | SULFENIC ACID-REACTIVE COMPOUNDS AND THEIR METHODS OF SYNTHESIS AND USE IN DETECTION OR ISOLATION OF SULFENIC ACID-CONTAINING COMPOUNDS | POOLE LESLIE B | 2010-12-16 | — | — | US | disclosed |
| US-7803630-B2 | Method for detecting target compounds containing sulfenic acids using new reagents | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2010-09-28 | — | — | US | disclosed |
| US-20080070261-A1 | SULFENIC ACID-REACTIVE COMPOUNDS | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2008-03-20 | — | — | US | disclosed |
| US-7294748-B2 | Sulfenic acid-reactive compounds and their methods of synthesis | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2007-11-13 | — | — | US | disclosed |
| WO-2006044364-A2 | SULFENIC ACID-REACTIVE COMPOUNDS AND THEIR METHODS OF SYNTHESIS AND USE IN DETECTION OR ISOLATION OF SULFENIC ACID-CONTAINING COMPOUNDS | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20060084173-A1 | Sulfenic acid-reactive compounds and their methods of synthesis and use in detection or isolation of sulfenic acid-containing compounds | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070261-A1 | SULFENIC ACID-REACTIVE COMPOUNDS | QSOX1, SQOR, PRDX1 | SLC16A3 3916/4885ALDH1A1 138/4885KDM4E 3725/4885 |
| US-20100317027-A1 | SULFENIC ACID-REACTIVE COMPOUNDS AND THEIR METHODS OF SYNTHESIS AND USE IN DETECTION OR ISOLATION OF SULFENIC ACID-CONTAINING COMPOUNDS | QSOX1, SQOR, TST | SLC16A3 4077/4885ALDH1A1 323/4885KDM4E 3681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.