Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269488 | 0.79 | EGFR (0.42) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6266311 | 0.78 | EGFR (0.44) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8436900 | 0.78 | EPHA2 (0.42) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8438071 | 0.77 | KDR (0.38) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5618725 | 0.76 | EHMT2 (0.51) | EGFRCSF1R | |
| SCHEMBL6268116 | 0.76 | EHMT2 (0.57) | — | |
| SCHEMBL6266172 | 0.74 | EGFR (0.46) | PDGFRBKDM4EALDH1A1TDP1EGFR | |
| SCHEMBL6266570 | 0.74 | EGFR (0.46) | RAF1EGFR | |
| SCHEMBL8444635 | 0.74 | EPHA2 (0.36) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3727488 | 0.74 | EGFR (0.49) | BRAFMETCHEK2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106188147-B | Pt complex containing quinazoline ligand as well as preparation method and application thereof | 中国科学院化学研究所 | 2021-08-20 | — | — | CN | disclosed |