Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KIF5B | P33176 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 2/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266311 | 0.90 | EGFR (0.44) | EGFRPDGFRBPDGFRAKDM4EALDH1A1 | |
| SCHEMBL6268116 | 0.84 | EHMT2 (0.57) | TLR9TLR7EHMT2EHMT1DNMT1 | |
| SCHEMBL8438071 | 0.83 | KDR (0.38) | EGFRPDGFRBPDGFRAKDM4EALDH1A1 | |
| SCHEMBL5618725 | 0.82 | EHMT2 (0.51) | EGFRTLR9TLR7EHMT2EHMT1 | |
| SCHEMBL8436900 | 0.82 | EPHA2 (0.42) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3727488 | 0.81 | EGFR (0.49) | EGFRRETAXLTLR9TLR7 | |
| SCHEMBL6266570 | 0.80 | EGFR (0.46) | EGFRPDPK1RETQPCTEHMT2 | |
| SCHEMBL8444662 | 0.80 | EPHA2 (0.44) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6266172 | 0.80 | EGFR (0.46) | EGFRPDGFRBKDM4EALDH1A1QPCT | |
| SCHEMBL11424 | 0.79 | PDGFRB (0.40) | EGFRPDGFRBPDGFRAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005048928-A2 | METHODS FOR TREATING VIRAL INFECTION | GEORGE MASON INTELLECTUAL PROPERTY (US) | 2005-06-02 | — | — | WO | disclosed |