Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5618725 | 0.83 | EHMT2 (0.51) | EGFRFGFR1FLT1KDR | |
| SCHEMBL6266311 | 0.81 | EGFR (0.44) | EGFRKDRALDH1A1PDGFRBTDP1 | |
| SCHEMBL6266570 | 0.80 | EGFR (0.46) | EGFRFGFR1FLT1KDRQPCT | |
| SCHEMBL6269488 | 0.80 | EGFR (0.42) | EGFRALDH1A1PDGFRBKDM4EQPCT | |
| SCHEMBL6268116 | 0.80 | EHMT2 (0.57) | — | |
| SCHEMBL3727488 | 0.78 | EGFR (0.49) | EGFRFGFR1FLT1KDRCYP2D6 | |
| SCHEMBL8436900 | 0.76 | EPHA2 (0.42) | FGFR1KDRALDH1A1PDGFRBKDM4E | |
| SCHEMBL8438071 | 0.76 | KDR (0.38) | EGFRKDRALDH1A1PDGFRBKDM4E | |
| SCHEMBL8444662 | 0.75 | EPHA2 (0.44) | KDRALDH1A1PDGFRBKDM4ECYP3A4 | |
| SCHEMBL11424 | 0.74 | PDGFRB (0.40) | EGFRALDH1A1PDGFRBTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005048928-A2 | METHODS FOR TREATING VIRAL INFECTION | GEORGE MASON INTELLECTUAL PROPERTY (US) | 2005-06-02 | — | — | WO | disclosed |