Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.46 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | FLT1 | P17948 | 2/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 3/20 | 0.43 |
| ▸ | RAF1 | P04049 | 3/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727488 | 0.96 | EGFR (0.49) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL5618725 | 0.92 | EHMT2 (0.51) | EGFRKDRFGFR1FLT1EPHA2 | |
| SCHEMBL6268116 | 0.87 | EHMT2 (0.57) | EHMT2EHMT1 | |
| SCHEMBL8436900 | 0.82 | EPHA2 (0.42) | KDRFGFR1EPHA2EPHB4EHMT2 | |
| SCHEMBL8438071 | 0.81 | KDR (0.38) | EGFRKDREPHA2EPHB4EHMT2 | |
| SCHEMBL8444662 | 0.80 | EPHA2 (0.44) | KDREPHA2EPHB4EHMT2EHMT1 | |
| SCHEMBL6266172 | 0.80 | EGFR (0.46) | EGFRKDRFGFR1FLT1QPCT | |
| SCHEMBL6269488 | 0.80 | EGFR (0.42) | EGFRPDPK1QPCTRETEHMT2 | |
| SCHEMBL6266311 | 0.79 | EGFR (0.44) | EGFRKDREHMT2EHMT1 | |
| SCHEMBL8444635 | 0.77 | EPHA2 (0.36) | KDRFLT1EPHA2EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005048928-A2 | METHODS FOR TREATING VIRAL INFECTION | GEORGE MASON INTELLECTUAL PROPERTY (US) | 2005-06-02 | — | — | WO | disclosed |