Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.44 |
| ▸ | KDR | P35968 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269488 | 0.90 | EGFR (0.42) | EGFRALDH1A1PDGFRBPDGFRAKDM4E | |
| SCHEMBL6268116 | 0.82 | EHMT2 (0.57) | EHMT2TLR9TLR7EHMT1 | |
| SCHEMBL8438071 | 0.81 | KDR (0.38) | EGFRKDRALDH1A1PDGFRBPDGFRA | |
| SCHEMBL5618725 | 0.81 | EHMT2 (0.51) | EGFRKDREHMT2TLR9TLR7 | |
| SCHEMBL6266172 | 0.81 | EGFR (0.46) | EGFRKDRALDH1A1PDGFRBKDM4E | |
| SCHEMBL8436900 | 0.80 | EPHA2 (0.42) | KDRALDH1A1PDGFRBPDGFRAKDM4E | |
| SCHEMBL3727488 | 0.80 | EGFR (0.49) | EGFRKDREHMT2TLR9TLR7 | |
| SCHEMBL6266570 | 0.79 | EGFR (0.46) | EGFRKDREHMT2EHMT1 | |
| SCHEMBL8444662 | 0.79 | EPHA2 (0.44) | KDRALDH1A1PDGFRBPDGFRAKDM4E | |
| SCHEMBL4357645 | 0.78 | EGFR (0.57) | EGFRKDRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005048928-A2 | METHODS FOR TREATING VIRAL INFECTION | GEORGE MASON INTELLECTUAL PROPERTY (US) | 2005-06-02 | — | — | WO | disclosed |