Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | GAPDH | P04406 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441378 | 0.85 | BRD4 (0.43) | KDM4EALDH1A1BRD4NPC1RAB9A | |
| SCHEMBL11441314 | 0.84 | BRD4 (0.52) | KDM4EALDH1A1BRD4SMN1; SMN2MAPT | |
| SCHEMBL11434522 | 0.82 | CNR2 (0.43) | ALDH1A1BRD4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11550329 | 0.81 | KMO (0.53) | KDM4EALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL11547644 | 0.81 | BRD4 (0.48) | KDM4EALDH1A1BRD4NPC1RAB9A | |
| SCHEMBL11434332 | 0.81 | BRD4 (0.40) | BRD4HSD17B10 | |
| SCHEMBL11178194 | 0.81 | BRD4 (0.40) | ALDH1A1BRD4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11429420 | 0.81 | GAA (0.49) | KDM4EALDH1A1BRD4NPC1RAB9A | |
| SCHEMBL11440224 | 0.81 | HSD17B10 (0.41) | KDM4EBRD4SMN1; SMN2NPSR1MAOB | |
| SCHEMBL11434380 | 0.79 | BAZ2B (0.36) | BAZ2BBAZ2ABRD4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |