Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398613 | 0.84 | MMP2 (0.44) | AGBL2CYP2C9HPGDCYP2C19MMP2 | |
| SCHEMBL11478885 | 0.83 | CYP2C9 (0.59) | AKR1B1LMNAAGBL2CYP2C9HPGD | |
| SCHEMBL30733478 | 0.79 | AKR1B1 (0.62) | AKR1B1LMNAGAAPOLBCYP2C9 | |
| SCHEMBL11551886 | 0.79 | AKR1B1 (0.62) | AKR1B1LMNAGAAPOLBCYP2C9 | |
| SCHEMBL11453265 | 0.79 | AGBL2 (0.50) | AKR1B1AGBL2CYP2C9HPGDCYP2C19 | |
| SCHEMBL11427396 | 0.77 | AKR1B1 (0.56) | AKR1B1LMNAGAAPOLBAGBL2 | |
| SCHEMBL11430842 | 0.77 | MMP2 (0.63) | AKR1B1LMNAGAAPOLBCYP2C9 | |
| SCHEMBL11400372 | 0.75 | MMP2 (0.38) | AGBL2CYP2C9HPGDCYP2C19MMP2 | |
| SCHEMBL11554657 | 0.75 | AKR1B1 (0.49) | AKR1B1LMNAGAAPOLBCYP2C9 | |
| SCHEMBL11407313 | 0.74 | AGBL2 (0.62) | AGBL2CYP2C9HPGDCYP2C19MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282245-A | ANTIINFLAMMATORY | NIPPON CHEMIPHAR CO., LTD. (JP) | 1981-08-04 | — | — | US | disclosed |