Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799203 | 0.81 | NPC1 (0.53) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL11146135 | 0.75 | MEN1 (0.48) | RAB9ANPC1TP53PNPLA2HDAC6 | |
| SCHEMBL11425817 | 0.74 | MTNR1A (0.51) | ALDH1A1L3MBTL1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10801844 | 0.74 | SIRT2 (0.56) | RAB9AKDM1AMAOBKMT2A | |
| SCHEMBL11151473 | 0.73 | BCHE (0.44) | ALDH1A1SMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL11360828 | 0.73 | LMNA (0.62) | ALDH1A1SMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL10807106 | 0.72 | NR1H4 (0.57) | SMN1; SMN2RAB9AHTTMTNR1AMTNR1B | |
| SCHEMBL11677076 | 0.71 | RAB9A (0.51) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL11630497 | 0.71 | SMN1; SMN2 (0.50) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL10806965 | 0.71 | PDK1 (0.61) | RAB9ANPC1CYP2D6MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242122-A | CARBAMOYL-OXY AND -THIO DERIVATIVES OF PHENYLUREA | MONSANTO COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| US-4013450-A | Herbicidal ureido containing carbanilates | MONSANTO COMPANY (US) | 1977-03-22 | — | — | US | disclosed |