Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428912 | 0.86 | BRD4 (0.46) | BRD4CREBBPHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL11439976 | 0.83 | KCNA3 (0.39) | HSD17B10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11554573 | 0.81 | ALDH1A1 (0.48) | BRD4CREBBPHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL11547644 | 0.81 | BRD4 (0.48) | BRD4CREBBPHSD17B10ALDH1A1LMNA | |
| SCHEMBL11441314 | 0.80 | BRD4 (0.52) | BRD4CREBBPHSD17B10ALDH1A1LMNA | |
| SCHEMBL11178194 | 0.80 | BRD4 (0.40) | BRD4MAOBHSD17B10ALDH1A1MEN1 | |
| SCHEMBL11549258 | 0.79 | BRD4 (0.44) | BRD4CREBBPMAOBHSD17B10ALDH1A1 | |
| SCHEMBL11549547 | 0.79 | BRD4 (0.44) | BRD4CREBBPMAOBHSD17B10ALDH1A1 | |
| SCHEMBL11434522 | 0.78 | CNR2 (0.43) | BRD4CREBBPMAOBALDH1A1LMNA | |
| SCHEMBL11441378 | 0.78 | BRD4 (0.43) | BRD4CREBBPHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |