Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 3/20 | 0.40 |
| ▸ | KLK1 | P06870 | 2/20 | 0.40 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427954 | 0.91 | RAB9A (0.43) | RAB9ANPC1CASP6CTDSP1KDR | |
| SCHEMBL11438676 | 0.88 | ALDH1A1 (0.42) | RAB9ACASP6CTDSP1PLGKLK1 | |
| SCHEMBL11438816 | 0.84 | APEX1 (0.50) | RAB9ANPC1CASP6CTDSP1KDR | |
| SCHEMBL11427487 | 0.83 | ALDH1A1 (0.42) | RAB9ACASP6CTDSP1HSD17B10TSHR | |
| SCHEMBL11436839 | 0.83 | KCNMA1 (0.52) | RAB9ANPC1KMT2ALMNAGAA | |
| SCHEMBL11426173 | 0.83 | RAB9A (0.43) | RAB9ANPC1CASP6KDRHSD17B10 | |
| SCHEMBL11426166 | 0.81 | CASP6 (0.64) | RAB9ANPC1CASP6CTDSP1PLG | |
| SCHEMBL11433794 | 0.81 | KCNMA1 (0.49) | RAB9ANPC1CASP6KMT2ALMNA | |
| SCHEMBL11440870 | 0.80 | RAB9A (0.47) | RAB9ANPC1KDRPLGKLK1 | |
| SCHEMBL11431273 | 0.80 | SNCA (0.43) | RAB9ANPC1KDRPLGKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |