Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428236 | 0.92 | LMNA (0.43) | OPRK1PDE4DALDH1A1MAPTKMT2A | |
| SCHEMBL11428247 | 0.87 | KMT2A (0.38) | OPRK1PDE4DALDH1A1MAPTKMT2A | |
| Lofendazam SCHEMBL1003371 | 0.86 | OPRK1 (0.51) | OPRK1PDE4DALDH1A1MAPTKMT2A | |
| SCHEMBL11420364 | 0.86 | L3MBTL1 (0.54) | OPRK1PDE4DALDH1A1MAPTKMT2A | |
| SCHEMBL11429879 | 0.86 | POLB (0.51) | ALDH1A1MAPTKMT2AGAALMNA | |
| SCHEMBL11431736 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTKMT2AGAALMNA | |
| SCHEMBL11434528 | 0.81 | AVPR1A (0.52) | OPRK1PDE4DALDH1A1MAPTKMT2A | |
| SCHEMBL11423308 | 0.79 | MAPT (0.46) | OPRK1PDE4DALDH1A1MAPTKMT2A | |
| SCHEMBL11422701 | 0.78 | LMNA (0.43) | OPRK1PDE4DALDH1A1KMT2ALMNA | |
| SCHEMBL11419566 | 0.77 | CNR1 (0.43) | MAPTKMT2AAVPR1AF7PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30293-E | Process for preparing 1,5-benzodiazepine-2-ones | KNOLL A.G. (DE) | 1980-06-03 | — | — | US | disclosed |