Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433973 | 0.88 | ALDH1A1 (0.48) | CASP6CTDSP1TTRHDAC1TDP1 | |
| SCHEMBL11340875 | 0.86 | TIMP3 (0.47) | CASP6CTDSP1TTRCA1CA2 | |
| SCHEMBL10907955 | 0.86 | CD40 (0.44) | CASP6CTDSP1TTRCA1CA2 | |
| SCHEMBL11433587 | 0.86 | CASP6 (0.49) | CASP6CTDSP1CA1CA2CA12 | |
| SCHEMBL11433615 | 0.85 | CASP6 (0.51) | CASP6CTDSP1CA1CA2CA12 | |
| SCHEMBL11433769 | 0.84 | TTR (0.43) | CASP6CTDSP1TTRTDP1MEN1 | |
| SCHEMBL11439440 | 0.84 | TTR (0.43) | CASP6CTDSP1TTRTDP1MEN1 | |
| SCHEMBL11424407 | 0.83 | CD40 (0.57) | CASP6CTDSP1CA1CA2TDP1 | |
| SCHEMBL11433094 | 0.82 | TTR (0.46) | CASP6CTDSP1TTRCA1CA2 | |
| Acetic Acid SCHEMBL11434117 | 0.82 | CASP6 (0.46) | CASP6CTDSP1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |