Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 3/20 | 0.44 |
| ▸ | CD40LG | P29965 | 3/20 | 0.44 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | FGF1 | P05230 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340875 | 0.93 | TIMP3 (0.47) | CD40CD40LGTNNI3TNNT2TNNC1 | |
| SCHEMBL10907950 | 0.88 | MEN1 (0.47) | TNNI3TNNT2TNNC1HKDC1TIMP3 | |
| SCHEMBL10909346 | 0.86 | CD40 (0.43) | CD40CD40LGTNNI3TNNT2TNNC1 | |
| SCHEMBL11435663 | 0.86 | CASP6 (0.48) | CD40CD40LGTNNI3TNNT2TNNC1 | |
| SCHEMBL10907905 | 0.86 | MPL (0.48) | CD40CD40LGTIMP3CTDSP1CASP6 | |
| SCHEMBL10908939 | 0.83 | CD40 (0.52) | CD40CD40LGTIMP3CTDSP1CASP6 | |
| SCHEMBL10907712 | 0.82 | MPL (0.46) | CD40CD40LGTIMP3CTDSP1CASP6 | |
| SCHEMBL11424407 | 0.82 | CD40 (0.57) | CD40CD40LGCTDSP1CASP6CA1 | |
| SCHEMBL10907596 | 0.82 | HPSE (0.42) | CD40CD40LGTIMP3KMT2AMEN1 | |
| SCHEMBL10907419 | 0.82 | BRAF (0.40) | TNNI3TNNT2TNNC1HKDC1TIMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |