Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179795 | 0.84 | ESR2 (0.46) | MPOCYP3A4APPALDH1A1ESR2 | |
| SCHEMBL4802603 | 0.80 | MPO (0.60) | MPOCYP3A4ALDH1A1LMNA | |
| SCHEMBL6789105 | 0.80 | PTPN1 (0.46) | MPOCYP3A4MEN1KMT2ABACE1 | |
| SCHEMBL12388903 | 0.80 | RARA (0.50) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL12389551 | 0.79 | CA1 (0.49) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8309725 | 0.78 | ESR1 (0.52) | MPOCYP3A4BACE1ESR2 | |
| SCHEMBL13384512 | 0.74 | CYP3A4 (0.37) | MPOCYP3A4BACE1ALDH1A1MAOB | |
| SCHEMBL12390128 | 0.74 | HTR7 (0.42) | BACE1PARP1PARP10 | |
| SCHEMBL14267917 | 0.73 | MPO (0.56) | MPOCYP3A4MEN1KMT2AMAPT | |
| SCHEMBL22685320 | 0.72 | TDP1 (0.38) | CYP3A4MEN1KMT2AGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399509-B2 | Glucopyranoside derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-19 | — | — | US | disclosed |
| EP-2260051-B1 | GLUCOPYRANOSIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-10-17 | — | — | EP | disclosed |
| US-20110028414-A1 | GLUCOPYRANOSIDE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG | 2011-02-03 | — | — | US | disclosed |
| EP-2260051-A1 | GLUCOPYRANOSIDE DERIVATIVES | Merck Patent GmbH (DE) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009124638-A1 | GLUCOPYRANOSIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028414-A1 | GLUCOPYRANOSIDE DERIVATIVES | UGGT1, SLC5A1, SLC5A2 | MPO 1913/4885CYP3A4 725/4885MEN1 3743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.